| Internal reflectivity of filtering blebs versus intraocular pressure in patients with recent trabeculectomy. | |
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MedLine Citation:
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PMID: 21228390 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The authors conducted a morphology analysis of filtering blebs with anterior segment optical coherence tomography (AS-OCT) in patients shortly after trabeculectomy to find further criteria for success or failure of a filtering bleb. METHODS: Thirty-seven patients (43 eyes) who had recently (<2 years) undergone trabeculectomy were measured 1 to 4 times with AS-OCT. In contrast to ultrasound biomicroscopy, AS-OCT eliminates the need for a water bath in contact with the globe. This is of particular value in a study of morphologic parameters that may be altered by contact and in the postoperative period when concerns of infection are paramount. In this study, the internal reflectivity of the fluid-filled cavity of the filtering bleb was compared with the intraocular pressure (IOP). RESULTS: Mean age of the patients was 69.5 years (range, 27-84 years). Average preoperative IOP of the 43 eyes was 20.6 mm Hg (range, 10-42 mm Hg), average postoperative IOP at the time of AS-OCT measurement was 10.6 mm Hg (range, 2-40 mm Hg), and mean IOP reduction was 10.0 mm Hg (48.5%). Internal reflectivity of the fluid-filled cavity of the filtering bleb correlated very well to the IOP (R(2) = 0.3762, n = 61, P < 0.0001). CONCLUSIONS: AS-OCT is a promising tool with which to analyze the morphology of the filtering bleb after trabeculectomy. A highly significant correlation between the internal reflectivity of the fluid-filled cavity of the filtering bleb and the IOP could be shown that may have future impact in evaluating the postoperative success or failure of filtering blebs. |
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Authors:
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Lukas Pfenninger; Fabienne Schneider; Jens Funk |
Publication Detail:
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Type: Journal Article Date: 2011-04-14 |
Journal Detail:
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Title: Investigative ophthalmology & visual science Volume: 52 ISSN: 1552-5783 ISO Abbreviation: Invest. Ophthalmol. Vis. Sci. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-04-15 Completed Date: 2011-06-22 Revised Date: 2013-01-09 |
Medline Journal Info:
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Nlm Unique ID: 7703701 Medline TA: Invest Ophthalmol Vis Sci Country: United States |
Other Details:
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Languages: eng Pagination: 2450-5 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, University Hospital Zurich, Zurich, Switzerland. lukas.pfenninger@ksw.ch |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Aqueous Humor / metabolism Conjunctiva / metabolism, pathology* Female Glaucoma / physiopathology, surgery* Humans Intraocular Pressure / physiology* Male Microscopy, Acoustic Middle Aged Surgically-Created Structures / pathology* Tomography, Optical Coherence Trabeculectomy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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