Document Detail


Internal exposure, effect monitoring, and lung function in welders after acute short-term exposure to welding fumes from different welding processes.
MedLine Citation:
PMID:  20798644     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: In this study, the effect of short-term exposure to welding fumes emitted by different welding techniques on workers was investigated.
METHODS: In a 3-fold crossover study, six welders used three different welding techniques for 3 hours. Before and after welding, blood and urine samples were collected to perform biomonitoring of metals. Breath condensate was collected to assess inflammatory reactions, and lung function measurements were performed.
RESULTS: Welding led to a significant increase of chromium and nickel in blood and urine and of nitrate and nitrite in exhaled breath condensate. These increases were higher for manual metal arc welding with alloyed material (MAW-a). Several lung function parameters decreased after welding. This decrease was significantly higher after MAW-a.
CONCLUSIONS: In respect to biological effects, MAW-a seems to be more important than other welding techniques.
Authors:
Peter Brand; Monika Gube; Kerstin Gerards; Jens Bertram; Heinz Kaminski; Astrid Christiane John; Thomas Kuhlbusch; Martin Wiemann; Christian Eisenbeis; Reinhard Winkler; Thomas Kraus
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine     Volume:  52     ISSN:  1536-5948     ISO Abbreviation:  J. Occup. Environ. Med.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-10     Completed Date:  2011-01-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504688     Medline TA:  J Occup Environ Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  887-92     Citation Subset:  IM    
Affiliation:
Institute for Occupational and Social Medicine, RWTH Aachen University, Aachen, Germany. PBrand@ukaachen.de
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MeSH Terms
Descriptor/Qualifier:
Adult
Air Pollutants, Occupational / toxicity*
Breath Tests
Chromium / blood,  urine
Cross-Over Studies
Environmental Monitoring
Humans
Iron / blood,  metabolism
Male
Middle Aged
Nickel / blood,  urine
Nitrates / analysis
Nitrites / analysis
Occupational Exposure / adverse effects*,  analysis*
Osteopontin / blood
Respiratory Function Tests
Respiratory Physiological Phenomena
Tyrosine / analogs & derivatives,  analysis
Welding / methods*
Young Adult
Chemical
Reg. No./Substance:
0/Air Pollutants, Occupational; 0/Nitrates; 0/Nitrites; 106441-73-0/Osteopontin; 3604-79-3/3-nitrotyrosine; 55520-40-6/Tyrosine; 7439-89-6/Iron; 7440-02-0/Nickel; 7440-47-3/Chromium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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