Document Detail


Intermittent spatio-temporal desynchronization and sequenced synchrony in ECoG signals.
MedLine Citation:
PMID:  19045505     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Electrocorticographic (ECoG) signals from the brain surface typically exhibit high synchrony across large cortical areas, interrupted by brief periods of desynchronization exhibiting propagating phase discontinuities, across which spatial patterns of phase emerge in selected frequency bands. Experiments with rabbits trained using classical conditioning paradigms indicated that such desynchronization periods demarcate cognitive processing in the subjects; the ECoG in the frames between such periods revealed spatial patterns of amplitude modulation that were classified with respect to sensory stimuli that the rabbits had been trained to recognize. The present work describes intermittent synchrony and desynchronization of ECoG signals measured over the visual cortex. We analyze the analytic amplitude (AA) and analytic phase (AP) of the signals bandpassed over the beta band (12.5-25 Hz) and theta band (3-7 Hz) using the Hilbert transform. The AP of analytic signals evaluated using a Shannon-based synchronization index in theta band exhibits phase synchronization for varying time periods averaging about 1 s, interrupted by desynchronization periods of duration about 0.1 s. Synchronization periods in the beta-band last <100 ms, with interruptions by desynchronization lasting one-tenth that, in which the analytic amplitude drops drastically. During these "null spikes," the analytic phase is undefined, and the spatial and temporal phase differences show high dispersion. Detailed examination of the bandpass filtered ECoG confirms the presence of a shared mean frequency in a frame of synchronized oscillation, at which frequency the spatial pattern of the AP has the form of a cone. Between frames the AA approaches zero. The form of the null spike resembles a tornado (a vortex), as shown in sequential frames by a rotating spatial pattern of amplitude in the filtered ECoG.
Authors:
Robert Kozma; Walter J Freeman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chaos (Woodbury, N.Y.)     Volume:  18     ISSN:  1089-7682     ISO Abbreviation:  Chaos     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-12-02     Completed Date:  2009-01-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100971574     Medline TA:  Chaos     Country:  United States    
Other Details:
Languages:  eng     Pagination:  037131     Citation Subset:  IM    
Copyright Information:
(c) 2008 American Institute of Physics.
Affiliation:
Computational NeuroDynamics Laboratory, University of Memphis, Memphis, Tennessee 38120, USA. rkozma@memphis.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Biological Clocks / physiology*
Computer Simulation
Evoked Potentials, Visual / physiology*
Models, Neurological*
Nerve Net / physiology*
Nonlinear Dynamics
Rabbits
Visual Cortex / physiology*
Visual Perception / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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