Document Detail


Intermittent hypoxia increases ventilation and Sa(O2) during hypoxic exercise and hypoxic chemosensitivity.
MedLine Citation:
PMID:  11247944     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was 1) to test the hypothesis that ventilation and arterial oxygen saturation (Sa(O2)) during acute hypoxia may increase during intermittent hypoxia and remain elevated for a week without hypoxic exposure and 2) to clarify whether the changes in ventilation and Sa(O2) during hypoxic exercise are correlated with the change in hypoxic chemosensitivity. Six subjects were exposed to a simulated altitude of 4,500 m altitude for 7 days (1 h/day). Oxygen uptake (VO2), expired minute ventilation (VE), and Sa(O2) were measured during maximal and submaximal exercise at 432 Torr before (Pre), after intermittent hypoxia (Post), and again after a week at sea level (De). Hypoxic ventilatory response (HVR) was also determined. At both Post and De, significant increases from Pre were found in HVR at rest and in ventilatory equivalent for O2 (VE/VO2) and Sa(O2) during submaximal exercise. There were significant correlations among the changes in HVR at rest and in VE/VO2 and Sa(O2) during hypoxic exercise during intermittent hypoxia. We conclude that 1 wk of daily exposure to 1 h of hypoxia significantly improved oxygenation in exercise during subsequent acute hypoxic exposures up to 1 wk after the conditioning, presumably caused by the enhanced hypoxic ventilatory chemosensitivity.
Authors:
K Katayama; Y Sato; Y Morotome; N Shima; K Ishida; S Mori; M Miyamura
Related Documents :
21188424 - Thermal comfort modelling of body temperature and psychological variations of a human e...
8183094 - Assessment of peripheral chemoreflex contributions to exercise hyperpnea in humans.
6735804 - Effects of hypoxia on ventilation during postnatal development in conscious kittens.
16401774 - Increased peripheral chemoreceptors sensitivity and exercise ventilation in heart trans...
22120964 - Epidemiology and diagnosis of heart failure with preserved left ventricular ejection fr...
21188424 - Thermal comfort modelling of body temperature and psychological variations of a human e...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  90     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-03-15     Completed Date:  2001-05-31     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1431-40     Citation Subset:  IM    
Affiliation:
Research Center of Health, Physical Fitness and Sports, Research Institute of Environmental Medicine, Nagoya University, Nagoya 464-8601, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Air Pressure
Anoxia / physiopathology*
Exercise / physiology*
Exercise Test
Heart Rate / physiology
Humans
Hypercapnia / physiopathology
Male
Oxygen / blood
Oxygen Consumption / physiology*
Respiratory Function Tests
Respiratory Mechanics / physiology*
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effects of vitamin E and alpha-lipoic acid on skeletal muscle contractile properties.
Next Document:  Respiratory dynamics during laughter.