Document Detail

Intermittent claudication: functional capacity and quality of life after exercise training or percutaneous transluminal angioplasty--systematic review.
MedLine Citation:
PMID:  15860674     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To systematically review published data about the short- and long-term effects of exercise training and angioplasty on functional capacity and quality of life of patients with intermittent claudication. MATERIALS AND METHODS: Articles published between January 1980 and February 2003 were included if patients had intermittent claudication treated with exercise training or angioplasty and if both functional capacity and quality-of-life scores from Medical Outcomes Study 36-Item Short Form health survey were reported for at least 3 months of follow-up. Data were pooled by using a random effects model and weighted means. Pooled results were compared between the treatment groups by using the chi2 test and the Student t test (alpha = .05, two sided). RESULTS: In the analyses, five studies (202 patients) were included in the exercise group, and three studies (470 patients), in the angioplasty group. At 3 months of follow-up, the ankle-brachial index was significantly improved in the angioplasty group (mean change, 0.18; P < .01) but not in the exercise group (mean change, 0.01; P = .29). At 3 months, quality of life was significantly improved with regard to ratings of physical functioning and bodily pain in the exercise group (mean change, 18 and 10, respectively; P < .01) and physical role functioning in the angioplasty group (mean change, 30; P = .03). Mean change in ankle-brachial index significantly differed between the two treatment groups at 3 and 6 months (P < .01); mean change in quality-of-life scores did not. CONCLUSION: Improvement in quality of life was demonstrated after both exercise training and angioplasty, whereas functional capacity showed significant improvement after angioplasty. The ankle-brachial index significantly differed between the two treatment groups at 3 and 6 months, whereas the quality-of-life scores did not.
Sandra Spronk; Johanna L Bosch; Hermanus F Veen; Pieter T den Hoed; M G Myriam Hunink
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Publication Detail:
Type:  Comparative Study; Journal Article; Review     Date:  2005-04-28
Journal Detail:
Title:  Radiology     Volume:  235     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-05-25     Completed Date:  2005-06-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  833-42     Citation Subset:  AIM; IM    
Copyright Information:
Copyright RSNA, 2005.
Vascular Laboratory and Department of Surgery, Ikazia Hospital, Rotterdam, The Netherlands.
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MeSH Terms
Angioplasty, Balloon*
Intermittent Claudication / therapy*
Quality of Life*
Recovery of Function
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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