Document Detail

Intermittent claudication: exercise-increased walking distance is not related to improved cardiopulmonary fitness.
MedLine Citation:
PMID:  15963739     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To assess if exercise training improves the symptoms of intermittent claudication by improvement in cardiopulmonary fitness. METHODS: Claudication distance (CD), maximum walking distance (MWD), calf endurance (repetitive heel raises), cardiovascular fitness (VO2 peak), and ankle-brachial pressure index (ABPI) were measured in 16 subjects with intermittent claudication before, and following an 8-week treadmill training programme. RESULTS: Training resulted in a median increase in CD of 65.5 m (p<0.01), MWD of 339.5 m (p<0.001) and HR of 19 (p<0.03). Notably, improvements in MWD correlated with those in HR (p=0.001; R=0.75). There was no training-associated change in VO2 peak (median increase of only 0.35 ml/kg/min; p=0.60) or ABPI (median increase of only 0.01; p=0.64). CONCLUSION: In this study, overall improvement in claudication was not related to an improvement in cardiopulmonary fitness.
P W K Ng; S J Hollingsworth; H Luery; T J Kumana; E J Chaloner
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery     Volume:  30     ISSN:  1078-5884     ISO Abbreviation:  Eur J Vasc Endovasc Surg     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-09-06     Completed Date:  2005-10-25     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9512728     Medline TA:  Eur J Vasc Endovasc Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  391-4     Citation Subset:  IM    
Department of Surgery, The Royal Free and University College Medical School, The Middlesex Hospital, Mortimer Street, London W1T 3AA, UK.
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MeSH Terms
Cardiovascular Physiological Phenomena*
Exercise Test
Heart Rate / physiology
Intermittent Claudication / therapy*
Middle Aged
Oxygen Consumption / physiology
Physical Fitness / physiology*
Walking / physiology*
Comment In:
Eur J Vasc Endovasc Surg. 2006 Apr;31(4):447-8; author reply 448-9   [PMID:  16427336 ]

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