| Intermediate neurodevelopmental outcome after repair of ventricular septal defect. | |
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MedLine Citation:
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PMID: 20971268 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Children with congenital heart disease are at risk for impaired neurodevelopmental outcome. Despite the high prevalence of ventricular septal defects relative to other cardiac defects, few studies have specifically examined this population. The purpose of this study was to provide data on the intermediate neurodevelopmental outcome for children after repair of a ventricular septal defect. METHODS: Neurodevelopmental outcome was assessed for 31 children using standardized tests of IQ, memory, visual-motor ability, and academic achievement. Standardized parent and teacher reports of behavioral and psychosocial functioning were also examined. Patients were grouped into younger (less than 6 years old; n = 18) and older (6 years and older; n = 13) cohorts. RESULTS: Full-scale IQ scores were within the normal range. Although most other domains of neurodevelopmental and behavioral functioning were comparable to normative data, patient functioning was lower than population norms in the areas of performance IQ for the younger cohort (90.6 ± 16.1; p = 0.023), visual memory for the older cohort (84.5 ± 15.3; p = 0.003), and visual-motor ability (87.9 ± 14.2; p < 0.001) and adaptive behavior (94.3 ± 15.3; p = 0.050) for the entire cohort. CONCLUSIONS: After repair of ventricular septal defects, children function within the normal range in most areas. Three of the four domains in which lower functioning was observed tap into visual cognitive abilities rather than verbal abilities. Lower mean scores in these areas were, however, generally within one standard deviation of the population mean, suggesting mild weaknesses rather than significant impairments. |
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Authors:
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Julie S Simons; Rochelle Glidden; David Sheslow; Christian Pizarro |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 90 ISSN: 1552-6259 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-25 Completed Date: 2010-11-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: Netherlands |
Other Details:
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Languages: eng Pagination: 1586-91 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Nemours Cardiac Center, A. I. duPont Hospital for Children, Wilmington, Delaware 19803, USA. jsimons@nemours.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Brain
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physiology* Child Child Development* Child, Preschool Cognition Female Heart Septal Defects, Ventricular / physiopathology, surgery* Humans Infant Intelligence Male Memory Treatment Outcome |
| Comments/Corrections | |
Comment In:
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Ann Thorac Surg. 2010 Nov;90(5):1591-2
[PMID:
20971269
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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