| Interleukin 10 and residual kidney function are associated with risk of vascular calcification in patients undergoing peritoneal dialysis. | |
| | |
MedLine Citation:
|
PMID: 21543018 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Aims: Vascular calcification is a common complication among dialysis patients and its pathogenesis involves a variety of factors. The roles of pro-inflammatory cytokines and residual kidney function (RKF) in peritoneal dialysis (PD) patients with vascular calcification have not been investigated. Materials and methods: 157 stable PD patients were enrolled. All patients had plain X-ray film examination including chest (posterior-anterior view, CXR) and pelvis. Vascular calcification was interpreted as calcified deposit over aortic arch and linear calcification of pelvic arteries. Relevant biochemical data, pro-inflammatory markers, and PD-related factors were measured and collected. Results: Vascular calcification prevalence in CXRs was higher than that in pelvis films (38.2% vs. 22.3%, p < 0.05). Patients with vascular calcification in CXR had higher incidence of calcification in pelvis films (p < 0.05). Only a minor portion (14.6%) had two calcification sites. Regression analysis revealed that age, PD duration, body mass index, and RKF were independent factors associated with vascular calcification in CXR. Age, diabetes, IL-10 and RKF were factors associated in pelvis films. Factors independently related to vascular calcification in both films were age, duration, diabetes, IL-10, and RKF. Conclusions: Besides traditional risk factors, IL-10 and RKF were important factors associated with vascular calcification in PD patients. |
| | |
Authors:
|
C-T Lee; Y-C Tsai; C-Y Su; H-Y Ng; C-Y Hsu; S-F Ko; T-C Chen; C-C Kuo; C-C Yang; T T-Y Chiou; W-C Lee; Y-K Yang; K-K Lam |
Related Documents
:
|
10922238 - Histopathologic features of the temporal bone in usher syndrome type i. 11049768 - Thrombocytopenic purpura associated with brucellosis: report of 2 cases and literature ... 21155878 - Functional mica-129 polymorphism and serum levels of soluble mica are correlated with u... 50628 - Solitary myeloma. a study of 10 black patients during an 8-year period. 11146858 - Reconstructing gloria: a narrative analysis of team meetings. 23105538 - Correlation between chemical components of billary calculi and bile & sera and bile of ... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Clinical nephrology Volume: 75 ISSN: 0301-0430 ISO Abbreviation: Clin. Nephrol. Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-05-05 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0364441 Medline TA: Clin Nephrol Country: Germany |
Other Details:
|
Languages: eng Pagination: 397-402 Citation Subset: IM |
Affiliation:
|
1Division of Nephrology, Department of Internal Medicine, Chang-Gung Memorial Hospital Kaohsiung Medical Center, Chang-Gung University College of Medicine, 2Department of Neurology, Kaohsiung Medical University, and 3Department of Radiology, Chang-Gung Memorial Hospital Kaohsiung Medical Center, Chang-Gung University College of Medicine, Kaohsiung, Taiwan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Fetuin-A, coronary artery calcification and outcome in maintenance hemodialysis patients.
Next Document: Impact of renal failure on metabolic bone parameters in a vitamin D-deficient patient cohort.