Document Detail

Interleukin 1.
MedLine Citation:
PMID:  2469399     Owner:  NLM     Status:  MEDLINE    
The last decade has witnessed a remarkable expansion in the understanding of the skin as an immunologic organ. A prime example of this is the discovery that keratinocytes can synthesize and secrete immunoregulatory and proinflammatory glycoproteins termed cytokines. Initial studies focused on interleukin 1-like molecules produced by keratinocytes, initially termed epidermal cell-derived thymocyte activating factor (ETAF). It is now clear that the functional activities described by the term ETAF are composed mainly of interleukin 1 alpha and interleukin 1 beta, although other epidermal cytokines may contribute to the biologic activity. The biologic properties of interleukin 1 are the basis of this review.
D N Sauder
Related Documents :
12359049 - Invasion of melanoma in double knockout mice lacking tenascin-x and tenascin-c.
1116119 - The effect of aging and interval between primary and secondary treatment in two-stage c...
16679309 - Chemopreventive effects of alpha-santalol on ultraviolet b radiation-induced skin tumor...
20074459 - Tnfalpha and its receptors in psoriatic skin, before and after treatment with etanercept.
11823539 - Development of atopic dermatitis-like skin lesions in stat6-deficient nc/nga mice.
117059 - The effects of uvb and 7, 12, dimethylbenz(alpha)anthracene (dmba) on epidermal melanoc...
7635519 - Defects in the regulation of anti-dna antibody production in aged lupus-prone (nzb x nz...
14980699 - Mitochondrial oxidative stress and increased seizure susceptibility in sod2(-/+) mice.
10651949 - Neutralizing antibodies to granulocyte-macrophage colony-stimulating factor, interleuki...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Archives of dermatology     Volume:  125     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  1989 May 
Date Detail:
Created Date:  1989-06-01     Completed Date:  1989-06-01     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  679-82     Citation Subset:  AIM; IM    
Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Epidermis / metabolism
Inflammation / metabolism
Interleukin-1* / metabolism,  physiology
Lymphocytes / immunology
Molecular Structure
Tumor Necrosis Factor-alpha / physiology
Reg. No./Substance:
0/Interleukin-1; 0/Tumor Necrosis Factor-alpha; 68238-35-7/Keratins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Continuous subcutaneous infusion of peplomycin in oral squamous carcinoma
Next Document:  Human spermatozoal nuclear maturity in normozoospermia and asthenozoospermia.