| Interleukin-1 levels in blister fluids of some skin diseases with blister formation. | |
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MedLine Citation:
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PMID: 2078919 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The interleukin-1 (IL-1) concentrations in 32 blister fluid samples from 26 patients with several bullous dermatoses were determined using a radioimmunoassay technique in order to investigate the relation between IL-1 levels and blister formation. In epidermolysis bullosa, cases with the recessive dystrophic type showed normal levels, but about half of the cases of the simplex type demonstrated high levels. In autoimmune bullous diseases a tendency to higher levels was observed, and especially a patient with herpes gestationis had remarkably high levels. The high IL-1 levels in 25% (3/12) of samples from burn patients are probably related to the severity of inflammation and the duration after bulla formation. Since the IL-1 levels showed no great change in time courses of days, observations in the shorter term, i.e. in the course of hours, will be more useful. |
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Authors:
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T Imaizumi; K Nomura; I Hashimoto; Y Sawada |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical physiology and biochemistry Volume: 8 ISSN: 0252-1164 ISO Abbreviation: Clin Physiol Biochem Publication Date: 1990 |
Date Detail:
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Created Date: 1991-04-26 Completed Date: 1991-04-26 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8305885 Medline TA: Clin Physiol Biochem Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 179-83 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Hirosaki University School of Medicine, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Autoimmune Diseases
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metabolism Blister / metabolism* Burns / metabolism Exudates and Transudates / metabolism* Female Humans Interleukin-1 / metabolism* Kinetics Pemphigoid Gestationis / metabolism Pregnancy Skin Diseases, Vesiculobullous / immunology, metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Interleukin-1 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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