| Interlaboratory Agreement and Handling Variability for Consistency of Results in Paired Serum Bile Acid Assays. | |
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MedLine Citation:
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PMID: 22186717 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Paired serum bile acid (SBA) samples from 30 dogs with presumptive hepatobiliary disease and 30 apparently healthy dogs were submitted to three diagnostic laboratories to validate agreement between these facilities. Sensitivities and specificities ranged from 50% to 70% and from 74% to 85%, respectively, for all laboratories. The κ index confirmed almost perfect agreement between laboratories. Variation in sample handling and processing by different laboratories should not be considered a primary factor when aberrant SBA values are encountered. Documenting agreement between laboratories is essential as inconsistencies could direct unnecessary medical or surgical intervention when patients are evaluated at different hospitals during the course of their disease. |
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Authors:
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Michelle Nanfelt; Catriona Macphail; Katie C Kennedy; Jens Eickhoff |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-20 |
Journal Detail:
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Title: Journal of the American Animal Hospital Association Volume: - ISSN: 1547-3317 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0415027 Medline TA: J Am Anim Hosp Assoc Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Clinical Sciences, James L. Voss Veterinary Medical Center, Colorado State University, Fort Collins, CO. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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