| Interictal rhythmical midline theta differentiates frontal from temporal lobe epilepsies. | |
| | |
MedLine Citation:
|
PMID: 18801040 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: We evaluated the role of interictal rhythmical midline theta (RMT) in the identification of frontal lobe epilepsy (FLE) and its differentiation from temporal lobe epilepsy (TLE) and nonepileptic controls. METHODS: We included 162 individuals in the study: 54 FLE patients, 54 TLE patients, and 54 nonepileptic controls. Continuous electroencephalographic (EEG)-video monitoring was performed in all individuals. Interictal RMT was included only if it occurred during definite awake states. RMT associated with drowsiness or mental activation and ictal RMT was excluded. RESULTS: We identified RMT significantly more frequently in FLE patients (48.1%, 26 of 54) than in TLE patients (3.7%, 2 of 54) (p < 0.01), and not in the control group. The average frequency was 6 Hz (range 5-7 Hz), and the average RMT bursts lasted 8 s (3-12 s). Interestingly, all mesial FLE patients (n = 4) (as established by invasive EEG recordings) showed RMT, whereas this was less frequently the case in the other FLE patients (44%, 22 of 50) (p = 0.03). Thirteen of our 54 patients with FLE (24%) did not have any interictal epileptiform discharges (IEDs), but RMT was observed in the majority of these patients (62%, 8 of 13). CONCLUSION: Interictal RMT is common and has a localizing value in patients with FLE, provided that conditions such as drowsiness and mental activation as confounding factors for RMT are excluded. RMT should be included in the evaluation of patients considered for resective epilepsy surgery. |
| | |
Authors:
|
Pedro Beleza; Ozgür Bilgin; Soheyl Noachtar |
Publication Detail:
|
Type: Journal Article Date: 2008-09-17 |
Journal Detail:
|
Title: Epilepsia Volume: 50 ISSN: 1528-1167 ISO Abbreviation: Epilepsia Publication Date: 2009 Mar |
Date Detail:
|
Created Date: 2009-03-25 Completed Date: 2009-04-13 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 2983306R Medline TA: Epilepsia Country: United States |
Other Details:
|
Languages: eng Pagination: 550-5 Citation Subset: IM |
Affiliation:
|
Epilepsy Center, Department of Neurology, University of Munich, Munich, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Diagnosis, Differential Diagnostic Imaging Dominance, Cerebral / physiology Electroencephalography* Epilepsy, Frontal Lobe / diagnosis, etiology, physiopathology*, surgery Epilepsy, Temporal Lobe / diagnosis, etiology, physiopathology*, surgery Evoked Potentials / physiology Female Frontal Lobe / physiopathology Hippocampus / physiopathology Humans Male Middle Aged Signal Processing, Computer-Assisted* Theta Rhythm* Video Recording* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Severe postictal laryngospasm as a potential mechanism for sudden unexpected death in epilepsy: a ne...
Next Document: Streptococcus suis stimulates ICAM-1 shedding from microvascular endothelial cells.