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Interfraction prostate rotation determined from in-room computerized tomography images.
MedLine Citation:
PMID:  21540013     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Fiducial markers (FMs) are commonly used as a correction technique for interfraction translations of the prostate. The aim of this investigation was to determine the magnitude of prostate rotations using 2 methods: FM coordinates and the anatomical border of the prostate and rectum. Daily computed tomography (CT) scans (n = 346) of 10 prostate cancer patients with 3 implanted FMs were acquired using the CT on rails. FM coordinates were used to determine rotation in the sagittal, transverse, and coronal planes, and CT contours of the prostate and rectum were used to determine rotation along the sagittal plane. An adaptive technique based on a subset of images (n = 6; planning and first 5 treatment CTs) to reduce systematic rotation errors in the sagittal plane was tested. The standard deviation (SD) of systematic rotation from FM coordinates was 7.6°, 7.7°, and 5.0° in the sagittal, transverse and coronal planes. The corresponding SD of random error was 10.2°, 15.8°, and 6.5°. Errors in the sagittal plane, determined from prostate and rectal contours, were 10.1° (systematic) and 7.7° (random). These results did not correlate with rotation computed from FM coordinates (r = -0.017; p = 0.753, n = 337). The systematic error could be reduced by 43% to 5.6° when the mean prostate position was estimated from 6 CT scans. Prostate rotation is a significant source of error that appears to be more accurately determined using the anatomical border of the prostate and rectum rather than FMs, thus highlighting the utility of CT image guidance.
Authors:
Rebecca Owen; Tomas Kron; Farshad Foroudi; Alvin Milner; Jennifer Cox; Gillian Duchesne
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Publication Detail:
Type:  Journal Article     Date:  2010-06-17
Journal Detail:
Title:  Medical dosimetry : official journal of the American Association of Medical Dosimetrists     Volume:  36     ISSN:  1873-4022     ISO Abbreviation:  Med Dosim     Publication Date:  2011  
Date Detail:
Created Date:  2011-05-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8908862     Medline TA:  Med Dosim     Country:  United States    
Other Details:
Languages:  eng     Pagination:  188-94     Citation Subset:  IM    
Copyright Information:
Copyright © 2011. Published by Elsevier Inc.
Affiliation:
Radiation Oncology Mater Center, South Brisbane, Queensland, Australia; Radiation Therapy Services, Peter MacCallum Cancer Centre, Victoria, Australia; School of Medical Radiation Sciences, University of Sydney, Lidcombe, New South Wales, Australia.
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