Document Detail


Interferon-α and zidovudine for relapsed/refractory adult T cell leukemia/lymphoma: case reports of Japanese patients.
MedLine Citation:
PMID:  21080125     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Combination therapy with interferon-α and zidovudine (IFN/AZT) has been regarded as standard care for acute and indolent (i.e., chronic and smouldering) ATL based on reports involving a limited number of patients. This treatment approach has not been evaluated in Japan, a major endemic area of this disease in the world. This is the first Japanese report of IFN/AZT for ATL. It is impossible to draw any definitive conclusion from this small study; however, IFN/AZT showed clear anti-ATL effects for refractory/relapsed ATL patients. This report would contribute for developing future ATL treatment in Japan.
Authors:
Kenji Ishitsuka; Hiroo Katsuya; Tomona Toyota; Masanao Ishizu; Naoko Kunami; Mana Fujita; Hidenori Sasaki; Yasushi Takamatsu; Masanobu Uchiyama; Haruo Fujikane; Kentaro Ogata; Shuuji Hara; Kazuo Tamura
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Publication Detail:
Type:  Journal Article     Date:  2010-11-16
Journal Detail:
Title:  International journal of hematology     Volume:  92     ISSN:  1865-3774     ISO Abbreviation:  Int. J. Hematol.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111627     Medline TA:  Int J Hematol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  762-4     Citation Subset:  IM    
Affiliation:
Division of Medical Oncology, Hematology and Infectious Disease, Fukuoka University, 7-45-1 Nanakuma Jonan, Fukuoka, 814-0180, Japan, kenjiishitsuka@fukuoka-u.ac.jp.
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