Document Detail


Interferon therapy for orbital infiltration secondary to Erdheim-Chester disease.
MedLine Citation:
PMID:  11730673     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To describe a 55-year-old male with Erdheim-Chester disease with bilateral orbital infiltration and visual loss who was successfully treated with interferon-alpha. METHODS: Interventional case report. RESULTS: The patient was treated with interferon-alpha and had an improvement in his clinical signs, including his visual acuity, after 4 weeks of interferon therapy. CONCLUSION: Interferon-alpha can be effective in the treatment of orbital infiltration secondary to Erdheim-Chester disease.
Authors:
B Esmaeli; A Ahmadi; R Tang; J Schiffman; R Kurzrock
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  132     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2001-12-03     Completed Date:  2002-01-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  945-7     Citation Subset:  AIM; IM    
Affiliation:
Ophthalmology Section, Department of Plastic Surgery, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA. besmaeli@mdanderson.org
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MeSH Terms
Descriptor/Qualifier:
Exophthalmos / diagnosis,  drug therapy,  etiology
Granuloma / complications,  diagnosis,  drug therapy*
Histiocytosis, Non-Langerhans-Cell / diagnosis,  drug therapy*,  etiology
Humans
Interferon-alpha / therapeutic use*
Magnetic Resonance Imaging
Male
Middle Aged
Orbital Diseases / diagnosis,  drug therapy*,  etiology
Osteosclerosis / radionuclide imaging
Technetium Tc 99m Medronate / diagnostic use
Visual Acuity
Xanthomatosis / complications,  diagnosis,  drug therapy*
Chemical
Reg. No./Substance:
0/Interferon-alpha; 63347-66-0/Technetium Tc 99m Medronate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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