Document Detail

Interferon-induced pulmonary sarcoidosis.
MedLine Citation:
PMID:  16163897     Owner:  NLM     Status:  MEDLINE    
A further new case of sarcoidosis associated with the use of interferon (IFN) in the classical treatment of chronic hepatitis C (CHC) is reported. During the last two years, more than 20 cases of interferon-induced sarcoidosis have been described in the literature and about half of these cases have involved CHC. Therefore this disorder appears more common than originally thought two years ago, possibly due to the more frequent use of interferon therapy and an improvement in the methods of diagnosis.
R Farah; R Farah; N Makhoul
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of clinical pharmacology and therapeutics     Volume:  43     ISSN:  0946-1965     ISO Abbreviation:  Int J Clin Pharmacol Ther     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-16     Completed Date:  2006-01-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9423309     Medline TA:  Int J Clin Pharmacol Ther     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  441-3     Citation Subset:  IM    
Department of Internal Medicine F, Western Galilee Hospital, RO.Box 21, Nahariya 22100, Israel.
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MeSH Terms
Antiviral Agents / adverse effects*
Bronchoalveolar Lavage
CD4-CD8 Ratio
Hepatitis C, Chronic / drug therapy*
Interferon Alfa-2a / adverse effects*
Macrophages / immunology
Respiratory Function Tests
Respiratory Sounds
Sarcoidosis, Pulmonary / chemically induced*,  physiopathology
Reg. No./Substance:
0/Antiviral Agents; 76543-88-9/Interferon Alfa-2a

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