| Interferon γ in patients with HIV/AIDS and suspicion or latent tuberculosis infection. | |
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MedLine Citation:
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PMID: 23339916 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: To assess the usefulness of IGRA test (QuantiFERON®-Cell mediated immune) compared with the tuberculin skin test. METHODS: A cross-sectional study was carried out in Mexico, 25 infected patients with HIV-AIDS and the suspicion or with latent tuberculous infection (LTBI) who were >18 years of age and without treatment for tuberculosis (TB), were enrolled in the study. RESULTS: Median cluster of differentiation (CD4) count was 364 cells/μ L and median HIV viral load was 50 copies/mL. Overall, 20 patients (80%) had at least one positive diagnostic test for LTBI: four (16%) had a positive tuberculin skin test and 19 (76%), a positive QuantiFERON®-tuberculosis. CONCLUSIONS: No agreement is found between the two diagnostic tests: k = -0.004, 95% confidence interval (-0.2219, 0.2210). Additional longitudinal studies among HIV-infected populations with high prevalence of TB are needed to further assess the usefulness of IGRAs in this patient population. |
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Authors:
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Guadalupe García-Elorriaga; Mayté Martínez-Velázquez; Verónica Gaona-Flores; Guillermo Del Rey-Pineda; César González-Bonilla |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Asian Pacific journal of tropical medicine Volume: 6 ISSN: 1995-7645 ISO Abbreviation: Asian Pac J Trop Med Publication Date: 2013 Feb |
Date Detail:
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Created Date: 2013-01-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101533720 Medline TA: Asian Pac J Trop Med Country: Singapore |
Other Details:
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Languages: eng Pagination: 135-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2013 Hainan Medical College. Published by Elsevier B.V. All rights reserved. |
Affiliation:
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Unidad de Investigación en Inmunología e Infectología, Centro Médico Nacional La Raza (CMNR), Instituto Mexicano del Seguro Social (IMSS) Mexico City, Mexico. Electronic address: gelorriaga@webtelmex.net.mx. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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