| Interferon beta but not glatiramer acetate therapy aggravates headaches in MS. | |
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MedLine Citation:
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PMID: 12196668 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Type and frequency of headaches during immunomodulatory therapy in MS were determined in 167 consecutive patients. In a prospective group of 65 patients beginning interferon beta therapy, headache frequency and duration increased in 18% of all and in 35% of patients with pre-existing headache by more than 50% during the first 6 months. In two retrospective groups, increased headache frequency was reported by 34% of 53 patients on interferon beta, but by only 6% of 49 patients during at least 6 months of glatiramer acetate therapy. |
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Authors:
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W Pöllmann; L-P Erasmus; W Feneberg; F Then Bergh; A Straube |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
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Title: Neurology Volume: 59 ISSN: 0028-3878 ISO Abbreviation: Neurology Publication Date: 2002 Aug |
Date Detail:
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Created Date: 2002-08-28 Completed Date: 2002-09-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0401060 Medline TA: Neurology Country: United States |
Other Details:
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Languages: eng Pagination: 636-9 Citation Subset: AIM; IM |
Affiliation:
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Marianne-Strauss-Klinik, Berg, Germany. WPoellmannMue@aol.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adjuvants, Immunologic
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administration & dosage,
adverse effects* Adult Aged Drug Administration Schedule Female Headache / chemically induced*, diagnosis Humans Immunosuppressive Agents / administration & dosage Interferon-beta / administration & dosage, adverse effects* Male Middle Aged Multiple Sclerosis / complications, drug therapy* Muscle Spasticity / etiology Pain Measurement / drug effects Peptides / administration & dosage* Prospective Studies Retrospective Studies |
| Chemical | |
Reg. No./Substance:
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0/Adjuvants, Immunologic; 0/Immunosuppressive Agents; 0/Peptides; 0/copolymer 1; 145155-23-3/interferon beta-1b; 145258-61-3/interferon beta 1a; 77238-31-4/Interferon-beta |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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