Document Detail

Interferon-alfa treatment of essential thrombocythemia during pregnancy.
MedLine Citation:
PMID:  17106162     Owner:  NLM     Status:  MEDLINE    
We report on 2 successful pregnancies in a young woman who has essential thrombocythemia. The platelet count remained well controlled with interferon-alfa administration together with acetylsalicylic acid in each pregnancy. The present case and the published series suggest that close monitoring of the platelet count is crucial and that interferon may be the preferred therapeutic option in the management of pregnancy in patients with essential thrombocythemia.
Toshiko Iwashita; Mayumi Fujitani; Yoshiaki Yamamoto; Tatsuya Katsurada; Yataro Yoshida
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-11-15
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  45     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2006  
Date Detail:
Created Date:  2006-11-19     Completed Date:  2007-01-04     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1161-4     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Takeda General Hospital, Kyoto.
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MeSH Terms
Anticoagulants / therapeutic use*
Aspirin / therapeutic use
Drug Therapy, Combination
Fetal Diseases / prevention & control
Immunologic Factors / therapeutic use*
Infant, Newborn
Interferon-alpha / therapeutic use*
Platelet Count
Pregnancy Complications, Hematologic / drug therapy*
Pregnancy Outcome
Thrombocythemia, Essential / drug therapy*
Thromboembolism / prevention & control
Reg. No./Substance:
0/Anticoagulants; 0/Immunologic Factors; 0/Interferon-alpha; 50-78-2/Aspirin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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