Document Detail

Interfacing living unicellular algae cells with biocompatible polyelectrolyte-stabilised magnetic nanoparticles.
MedLine Citation:
PMID:  20641044     Owner:  NLM     Status:  MEDLINE    
Green algae are a promising platform for the development of biosensors and bioelectronic devices. Here we report a reliable single-step technique for the functionalisation of living unicellular green algae Chlorella pyrenoidosa with biocompatible 15 nm superparamagnetic nanoparticles stabilised with poly(allylamine hydrochloride). The magnetised algae cells can be manipulated and immobilised using external permanent magnets. The distribution of the nanoparticles on the cell walls of C. pyrenoidosa was studied by optical and fluorescence microscopy, TEM, SEM and EDX spectroscopy. The viability and the magnetic properties of the magnetised algae are studied in comparison with the native cells. The technique may find a number of potential applications in biotechnology and bioelectronics.
Rawil F Fakhrullin; Lubov V Shlykova; Alsu I Zamaleeva; Danis K Nurgaliev; Yuri N Osin; Javier García-Alonso; Vesselin N Paunov
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Macromolecular bioscience     Volume:  10     ISSN:  1616-5195     ISO Abbreviation:  Macromol Biosci     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-20     Completed Date:  2011-01-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101135941     Medline TA:  Macromol Biosci     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1257-64     Citation Subset:  IM    
Biomaterials and Nanomaterials Group, Department of Biochemistry, Kazan (Idel-Ural) Federal University, Kreml uramı 18, Kazan, Republic of Tatarstan.
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MeSH Terms
Biocompatible Materials / chemistry
Biosensing Techniques
Chlorella / cytology*
Materials Testing
Nanoparticles / chemistry*
Polymers / chemistry*
Reg. No./Substance:
0/Biocompatible Materials; 0/Polymers

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