Document Detail

Interface dermatitis along Blaschko lines.
MedLine Citation:
PMID:  25353350     Owner:  NLM     Status:  Publisher    
Linear dermatoses are fascinating entities that likely reflect embryologically derived cutaneous mosaicism, even when they present outside of childhood. Adult blaschkitis is a rare, relapsing inflammatory dermatitis that most often presents in middle age. It presents clinically as a pruritic eruption of linear papules, vesicles, and plaques, and is most commonly found to have features of spongiotic dermatitis on pathology. However, the clinical and histopathologic presentation of lichen striatus in adults may be similar to adult blaschkitis. We present a case in which 'blaschkitis' was suspected clinically, but the biopsy was noted to have non-characteristic microscopic features resembling erythema multiforme-a finding rarely reported in the literature to date. We present this case and a brief review of the most common acquired linear eruptions following Blaschko lines with the goal of expanding the histopathologic findings that may be encountered in adult blaschkitis. Moreover, the clinical and histopathologic overlap between the entities of blaschkitis and lichen striatus is explored, with acknowledgement that these entities may exist on a clinicopathologic spectrum. In the diagnosis of linear eruptions, clinicopathologic correlation is important for arriving at an accurate final diagnosis.
Mariah Johnson; Daniel Walker; William Galloway; Jerad M Gardner; Sara Shalin
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-10-29
Journal Detail:
Title:  Journal of cutaneous pathology     Volume:  -     ISSN:  1600-0560     ISO Abbreviation:  J. Cutan. Pathol.     Publication Date:  2014 Oct 
Date Detail:
Created Date:  2014-10-29     Completed Date:  -     Revised Date:  2014-10-30    
Medline Journal Info:
Nlm Unique ID:  0425124     Medline TA:  J Cutan Pathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
This article is protected by copyright. All rights reserved.
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