Document Detail

Interest of the attenuation coefficient in multiparametric high frequency ultrasound investigation of whole blood coagulation process.
MedLine Citation:
PMID:  19173438     Owner:  NLM     Status:  MEDLINE    
Previous studies [R. Libgot, F. Ossant, Y. Gruel, P. Lermusiaux, and F. Patat, Proc.-IEEE Utrason. Symp. 4, 2259-2262 (2005); R. Libgot-Calle, F. Ossant, Y. Gruel, P. Lermusiaux, and F. Patat, Ultrasound Med. Biol. 34, 252-264 (2008); F. Ossant, R. Libgot, P. Coupe, P. Lermusiaux, and F. Patat, Proc.-IEEE Ultrason. Symp. 2, 846-849 (2004)] showed the potential of an in vitro high frequency ultrasound (beyond 20 MHz) device to describe the blood clotting process. The parameters were simultaneously estimated in double transmission (DT) with the calculation of the velocity of longitudinal waves and in backscattering (BS) modes with the estimation of the integrated BS coefficient and the effective scatterer size. The aim of the present study was to show how the integrated attenuation coefficient (IAC) assessed in DT mode could provide additional information on this process, especially regarding the fibrin polymerization which is an important part of the coagulation process. A characteristic time t(a) of the variations in IAC that could be linked to fibrin formation was identified.
Rachel Callé; Camille Plag; Frédéric Patat; Frédéric Ossant
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of the Acoustical Society of America     Volume:  125     ISSN:  1520-8524     ISO Abbreviation:  J. Acoust. Soc. Am.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2009-01-28     Completed Date:  2009-07-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503051     Medline TA:  J Acoust Soc Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  530-8     Citation Subset:  IM    
Universite Francois Rabelais, INSERM U930, CNRS 2448 FRE, Tours, France.
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MeSH Terms
Blood Coagulation / physiology*
Equipment Design
Models, Biological
Ultrasonography* / instrumentation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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