| Interdigitating dendritic cell sarcoma of the tonsil. | |
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MedLine Citation:
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PMID: 20887493 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Interdigitating dendritic cell sarcoma (IDCS) is an extremely rare malignancy derived from antigen-presenting cells, with 55 cases reported thus far. A standard treatment modality is still being debated. This report describes a 56-year-old female who presented with right tonsillar enlargement and right submandibular swelling for 6 months. Treatment with empiric antibiotics did not result in improvement of her symptoms. Fine needle aspiration of the tonsil revealed no malignant cells. Tonsillectomy was eventually performed due to persistent symptoms. Based on microscopic findings, immunohistochemical stains, and review of the literature, the present case was finally diagnosed as IDCS of the tonsil with cervical lymph node involvement. The patient received four cycles of CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone) chemotherapy, and a clinically complete response was achieved followed by adjuvant radiation. |
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Authors:
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Sun Young Kim; Jin-Hyoung Kang; Sang Hoon Chun; Myung Hee Chang; Yeon-Sil Kim; Sang Nam Lee; Min-Sik Kim; Chang-Suk Kang |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Asia-Pacific journal of clinical oncology Volume: 6 ISSN: 1743-7563 ISO Abbreviation: Asia Pac J Clin Oncol Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-10-04 Completed Date: 2011-01-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101241430 Medline TA: Asia Pac J Clin Oncol Country: Australia |
Other Details:
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Languages: eng Pagination: 144-8 Citation Subset: IM |
Affiliation:
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Medical Oncology, The Catholic University of Korea, Seoul St Mary's Hospital, Seoul, Korea. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antineoplastic Combined Chemotherapy Protocols
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therapeutic use Combined Modality Therapy Cyclophosphamide / therapeutic use Dendritic Cell Sarcoma, Interdigitating / metabolism, pathology*, therapy Doxorubicin / therapeutic use Female Humans Immunohistochemistry Middle Aged Prednisone / therapeutic use Radiotherapy, Adjuvant Tonsillar Neoplasms / metabolism, pathology*, therapy Tonsillectomy Vincristine / therapeutic use |
| Chemical | |
Reg. No./Substance:
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23214-92-8/Doxorubicin; 50-18-0/Cyclophosphamide; 53-03-2/Prednisone; 57-22-7/Vincristine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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