Document Detail


Interconversion of F430 derivatives of methanogenic bacteria.
MedLine Citation:
PMID:  3421667     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
F430 is the prosthetic group of the methylcoenzyme M reductase of methanogenic bacteria. The compound isolated from Methanosarcina barkeri appears to be identical to the one obtained from the only distinctly related Methanobacterium thermoautotrophicum. F430 is thermolabile and in the presence of acetonitrile or C10-4 two epimerization products are obtained upon heating; in the absence of these compounds F430 is oxidized to 12,13-didehydro-F430. The latter is stereoselectively reduced under H2 atmosphere to F430 by cell-free extracts of M. barkeri or M. thermoautotrophicum. H2 may be replaced by the reduced methanogenic electron carrier coenzyme F420.
Authors:
J T Keltjens; J M Hermans; G J Rijsdijk; C van der Drift; G D Vogels
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Antonie van Leeuwenhoek     Volume:  54     ISSN:  0003-6072     ISO Abbreviation:  Antonie Van Leeuwenhoek     Publication Date:  1988  
Date Detail:
Created Date:  1988-10-17     Completed Date:  1988-10-17     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0372625     Medline TA:  Antonie Van Leeuwenhoek     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  207-20     Citation Subset:  IM    
Affiliation:
Dept. of Microbiology, Faculty of Science, University of Nijmegen, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Chromatography, High Pressure Liquid
Coenzymes / isolation & purification,  metabolism*
Dithionite
Euryarchaeota / enzymology*
Heating
Hydrogen / metabolism
Metalloporphyrins*
Metalloproteins / isolation & purification,  metabolism*
Nickel / isolation & purification,  metabolism*
Oxidation-Reduction
Riboflavin / analogs & derivatives,  metabolism
Spectrophotometry
Stereoisomerism
Zinc
Chemical
Reg. No./Substance:
0/Coenzymes; 0/Metalloporphyrins; 0/Metalloproteins; 1333-74-0/Hydrogen; 14844-07-6/Dithionite; 64885-97-8/coenzyme F420; 73145-13-8/factor F430; 7440-02-0/Nickel; 7440-66-6/Zinc; 83-88-5/Riboflavin; 98971-74-5/12,13-didehydro-F430

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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