Document Detail

Intercellular transfer of cell-surface proteins is common and can affect many stages of an immune response.
MedLine Citation:
PMID:  17290299     Owner:  NLM     Status:  MEDLINE    
Cells can extend the limits of their transcriptome by using proteins captured from other cells. Through an exchange of specific proteins, tools and information can be shared to establish integrated communities of cells that are better able to coordinate stages of an immune response. Transferred proteins can also contribute to pathology by allowing, for example, infection of cell types not otherwise infected. Here, I present the case for considering the intercellular transfer of cell-surface proteins between immune cells as commonplace and important.
Daniel M Davis
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2007-02-09
Journal Detail:
Title:  Nature reviews. Immunology     Volume:  7     ISSN:  1474-1733     ISO Abbreviation:  Nat. Rev. Immunol.     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-02-23     Completed Date:  2007-04-10     Revised Date:  2014-10-28    
Medline Journal Info:
Nlm Unique ID:  101124169     Medline TA:  Nat Rev Immunol     Country:  England    
Other Details:
Languages:  eng     Pagination:  238-43     Citation Subset:  IM    
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MeSH Terms
Biological Transport, Active / genetics,  immunology
Cell Communication / genetics,  immunology*
Extracellular Space / genetics,  immunology*
Immunity* / genetics
Membrane Proteins / genetics,  metabolism*
Grant Support
BB/I013407/2//Biotechnology and Biological Sciences Research Council; G0500563//Medical Research Council; G1001044//Medical Research Council
Reg. No./Substance:
0/Membrane Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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