| Interactions between vasopressin and food restriction on stress-induced analgesia. | |
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MedLine Citation:
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PMID: 8822511 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To investigate the role of the hormone vasopressin (VP) in mediating the response of an organism to food restriction stress-induced analgesia, tail flick latencies and scored qualitative behavioral responses were recorded in VP-containing (LE) rats and VP-deficient (DI) rats. These variables were measured under nonstressed (ad lib) and stressed (food restriction) conditions. In the ad lib condition, DI and LE rats had a similar tail flick latency and scored qualitative behavioral response to the stimulus eliciting the tail flick. During the food restriction condition, however, LE animals developed significant food restriction stress-induced analgesia, as measured by tail flick latency. On the other hand, DI animals did not develop significant analgesia. In addition, DI animals exhibited a significantly greater scored qualitative behavioral response to the stimulus eliciting the tail flick than LE animals. These results demonstrate that VP plays an important role in the regulation of food restriction stress-induced analgesia, as well as the scored qualitative behavioral response elicited by the tail flick stimulus. |
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Authors:
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C H Wideman; H M Murphy; S B McCartney |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Peptides Volume: 17 ISSN: 0196-9781 ISO Abbreviation: Peptides Publication Date: 1996 |
Date Detail:
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Created Date: 1996-12-10 Completed Date: 1996-12-10 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8008690 Medline TA: Peptides Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 63-6 Citation Subset: IM |
Affiliation:
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Department of Biology, John Carroll University, Cleveland, OH 44118, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Analgesia* Animals Food Deprivation / physiology* Male Neurosecretory Systems / physiopathology Pain / physiopathology* Pain Measurement Rats Rats, Brattleboro Stress, Physiological / physiopathology* Vasopressins / physiology* |
| Chemical | |
Reg. No./Substance:
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11000-17-2/Vasopressins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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