Document Detail

Interaction of glucose signals between the nucleus of the vagus nerve and the portal vein area in the regulation of gastric motility in rats.
MedLine Citation:
PMID:  8124586     Owner:  NLM     Status:  MEDLINE    
Intragastric pressures were examined after glucose injection into the nucleus of the vagus nerve (X) of the medulla oblongata or into the portal vein (PV) or both in bilaterally adrenalectomized rats. Ten mM glucose (500 nl) injected into the X or into the PV (25 microliters) decreased gastric pressure associated with insulin-hypoglycemia. Simultaneous injection of glucose into the X and PV produced a reduction in gastric pressure in an additive manner. In addition, a significant fall in gastric pressure was seen when an ineffective concentration of glucose was injected into the X and PV simultaneously. The results suggest that the X and PV signals interact with each other to inhibit gastric motility.
T Sakaguchi; T Aono; M Ohtake; N Sandoh
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Brain research bulletin     Volume:  33     ISSN:  0361-9230     ISO Abbreviation:  Brain Res. Bull.     Publication Date:  1994  
Date Detail:
Created Date:  1994-04-13     Completed Date:  1994-04-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7605818     Medline TA:  Brain Res Bull     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  469-71     Citation Subset:  IM    
Department of Physiology, Niigata University School of Medicine, Japan.
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MeSH Terms
Blood Glucose / metabolism
Gastrointestinal Motility / physiology*
Glucose / physiology*
Insulin / blood
Medulla Oblongata / physiology*
Portal Vein / physiology*
Rats, Wistar
Vagus Nerve / physiology*
Reg. No./Substance:
0/Blood Glucose; 11061-68-0/Insulin; 50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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