Document Detail


Interaction of fibrinolysis and prothrombotic risk factors in neonates, infants and children with and without thromboembolism and underlying cardiac disease. a prospective study.
MedLine Citation:
PMID:  11457466     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CONCLUSION: Data of this study indicate that neonates and infants with underlying cardiac disease and basically increased PAI-1 due to the 4G/4G variant of the PAI-1 promoter polymorphism along with elevated t-PA levels in combination with further prothrombotic risk factors are at high risk of developing early thromboembolism during cardiac catheterisation.
Authors:
U Nowak-Göttl; S Kotthoff; E Hagemeyer; R Junker; H G Kehl; H Vielhaber; D Kececioglu
Related Documents :
15151586 - Infant bath seats, drowning and near-drowning.
9122076 - Treatment with bifonazole shampoo for scalp seborrhea in infants and young children.
20863156 - A new hemostatic agent--ankaferd blood stopper: management of gastrointestinal bleeding...
21087706 - Randomized, controlled trial of individualized heparin and protamine management in infa...
21147386 - Neuromotor outcomes in infants with bronchopulmonary dysplasia.
7062166 - Clostridia isolated from the feces of infants during the first year of life.
Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study    
Journal Detail:
Title:  Thrombosis research     Volume:  103     ISSN:  0049-3848     ISO Abbreviation:  Thromb. Res.     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-07-17     Completed Date:  2001-12-04     Revised Date:  2014-07-28    
Medline Journal Info:
Nlm Unique ID:  0326377     Medline TA:  Thromb Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  93-101     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
3' Untranslated Regions / genetics
Adolescent
Cardiac Catheterization / adverse effects*
Case-Control Studies
Catheterization, Central Venous / adverse effects
Catheters, Indwelling / adverse effects
Child
Child, Preschool
Factor V / genetics
Fibrinolysis*
Gene Frequency
Genetic Predisposition to Disease
Genotype
Germany / epidemiology
Heart Defects, Congenital / blood*,  surgery
Humans
Infant
Infant, Newborn
Lipoprotein(a) / genetics
Plasminogen Activator Inhibitor 1 / genetics,  physiology*
Polymorphism, Genetic
Prevalence
Promoter Regions, Genetic / genetics
Prospective Studies
Protein C Deficiency / epidemiology,  genetics
Prothrombin / genetics
Risk Factors
Thromboembolism / epidemiology*,  etiology
Thrombophilia / epidemiology*,  genetics
Tissue Plasminogen Activator / physiology*
Chemical
Reg. No./Substance:
0/3' Untranslated Regions; 0/Lipoprotein(a); 0/Plasminogen Activator Inhibitor 1; 0/factor V Leiden; 9001-24-5/Factor V; 9001-26-7/Prothrombin; EC 3.4.21.68/Tissue Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Antiplatelet and anticoagulant effects of "HN-11 500," a selective thromboxane receptor an...
Next Document:  PAI-I 4G/5G polymorphism and sudden cardiac death in patients with coronary artery disease.