Document Detail

Interaction of exercise and age on substrates of carbohydrate metabolism.
MedLine Citation:
PMID:  8500818     Owner:  NLM     Status:  MEDLINE    
Changes in blood lactate, pyruvate, glucose and tissue glycogen were used as indices to evaluate the extent of effects of physical conditioning in young and old male rats. Rats were trained on a running wheel and swimming tank for 10 weeks. Biochemical estimations of lactic acid (LA) pyruvic acid (PA) and glucose (GL) in plasma and glycogen in cardiac and slow-twitch soleus (SOL) and fast-twitch extensor digitorum longus (EDL) skeletal muscles of trained animals were conducted and compared with those of sedentary control rats. Blood parameters showed a decrease upon training in both young and old rats, though of variable significances, between exercise types. Glycogen levels in the cardiac and skeletal muscles increased in all groups with the exception in SOL of older trained animals. Hepatic glycogen exhibited an insignificant increase in all groups. Results suggest that, though the trends of responses of both young and old rats to exercise follow a comparable path, the magnitudes of changes are definitely impressed upon appreciably by increasing age.
R Bhagavathi; S A Devi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of experimental biology     Volume:  31     ISSN:  0019-5189     ISO Abbreviation:  Indian J. Exp. Biol.     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-06-30     Completed Date:  1993-06-30     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0233411     Medline TA:  Indian J Exp Biol     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  72-5     Citation Subset:  IM    
Department of Zoology, Bangalore University, India.
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MeSH Terms
Aging / metabolism
Blood Glucose / metabolism
Carbohydrate Metabolism*
Glycogen / metabolism
Lactates / blood
Lactic Acid
Physical Exertion / physiology*
Pyruvates / blood
Pyruvic Acid
Rats, Wistar
Reg. No./Substance:
0/Blood Glucose; 0/Lactates; 0/Pyruvates; 127-17-3/Pyruvic Acid; 50-21-5/Lactic Acid; 9005-79-2/Glycogen

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