Document Detail

Interaction between anemia and blood levels of iron, zinc, copper, cadmium and lead in children.
MedLine Citation:
PMID:  17901668     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Anemia is a widespread problem among infants and children in many parts of the world, and it is often associated with some trace elements (iron, zinc, copper) and heavy metals (cadmium and lead). Aim of this study was to investigate the relationship between anemia and these elements. METHODS: This research was performed on 256 children (mean age 6.8 +/- 0.2) living in Denizli city center. We observed iron deficiency anemia (IDA) in 23 children, iron deficiency without anemia (ID) in 36 children and only anemia (ferritin level normal) (OA) in 18 children, and 179 children were found healthy and they were regarded as controls (C). Blood samples were taken from subjects and the concentrations of zinc, copper, iron, cadmium and lead in serum were measured with atomic absorption spectrophotometer. RESULTS: The levels of copper, cadmium and lead in serum were significantly higher in children with IDA than those of controls (p<0.05, p<0.05, p<0.01, respectively). The other elements in the serum of ID were not different from controls. CONCLUSION: High copper, cadmium and lead decreased iron absorption and negatively affected hematological parameters.
Sebahat Turgut; Aziz Polat; Murat Inan; Gunfer Turgut; Gulten Emmungil; Mevlut Bican; Tugrul Yasin Karakus; Osman Genc
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Indian journal of pediatrics     Volume:  74     ISSN:  0973-7693     ISO Abbreviation:  Indian J Pediatr     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-09-28     Completed Date:  2007-11-08     Revised Date:  2009-07-15    
Medline Journal Info:
Nlm Unique ID:  0417442     Medline TA:  Indian J Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  827-30     Citation Subset:  IM    
Department of Physiology, Pamukkale University Faculty of Medicine, Denizli, Turkey.
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MeSH Terms
Analysis of Variance
Anemia / blood*
Anemia, Iron-Deficiency / blood
Cadmium / blood
Copper / blood
Iron / blood
Lead / blood
Spectrophotometry, Atomic
Statistics, Nonparametric
Trace Elements / blood*
Zinc / blood
Reg. No./Substance:
0/Trace Elements; 7439-89-6/Iron; 7439-92-1/Lead; 7440-43-9/Cadmium; 7440-50-8/Copper; 7440-66-6/Zinc

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