Document Detail


Interaction between age and aerobic fitness in determining heart rate dynamics.
MedLine Citation:
PMID:  22551657     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Heart rate variability (HRV) and phase-rectified signal averaging (PRSA) estimates of heart rate dynamics are diminished in older people compared with younger people. However, it is not fully elucidated whether these differences are related to age per se or to the concomitant influence of aerobic fitness. Aerobic fitness (peak oxygen uptake, gas exchange threshold, oxygen uptake kinetics, exercise economy) was assessed in 70 healthy adults (41 male) aged 18-57 years. Participants also underwent a 24 h, ambulatory ECG for the derivation of HRV and PRSA variables. HRV was most sensitive to age and aerobic fitness when measured during the morning period (6 am-12 pm). HRV and PRSA were both diminished with age and were higher in aerobically superior participants. The decline in HRV with age was predominantly attributable to age itself (33%), with aerobic fitness representing an additional modulating factor. The present study also provides tentative evidence that assessment of the influence of aerobic fitness should not rely on [Formula: see text]O(2peak) alone. These findings demonstrate that age per se is an important factor in determining HRV. However, given the clinical importance of diminished HRV and the immutable nature of aging, the potential significance of physical activity/training to enhance cardiac regulatory function should not be underestimated.
Authors:
M A McNarry; M J Lewis
Related Documents :
1752997 - The microflora of periodontal sites showing active destructive progression.
22411717 - Heart rate variability abnormalities in young patients with dilated cardiomyopathy.
22298167 - Aging reduces left atrial performance during adrenergic stress in middle aged and older...
1062357 - Caries control through the use of sugar substitutes.
4584047 - Pathogenesis of marek's disease in old chickens: lesion regression as the basis for age...
675127 - Variations in lh and fsh serum gonadotropins in the hypophyseal chromophobe adenoma and...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-03
Journal Detail:
Title:  Physiological measurement     Volume:  33     ISSN:  1361-6579     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9306921     Medline TA:  Physiol Meas     Country:  -    
Other Details:
Languages:  ENG     Pagination:  901-914     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Clinical significance of minimal residual disease detected by multidimensional flow cytometry: Seria...
Next Document:  The prospective relationship between sleep problems and suicidal behavior in the National Longitudin...