Document Detail

Interaction of EDTA with tributyltin induced cellular toxicity.
MedLine Citation:
PMID:  2517269     Owner:  NLM     Status:  MEDLINE    
Tributyltin inhibited the growth of cells in concentration dependent manner. The inhibitory effect of tributyltin on E. coli was enhanced in the presence of metal ion chelator, EDTA. This was due to EDTA induced increase of permeability of bacterial cell envelope to tributyltin. In case of EDTA treated cells the rate of uptake of tributyltin was more pronounced as compared to control.
K Singh; L Joshi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of experimental biology     Volume:  27     ISSN:  0019-5189     ISO Abbreviation:  Indian J. Exp. Biol.     Publication Date:  1989 Sep 
Date Detail:
Created Date:  1990-05-24     Completed Date:  1990-05-24     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  0233411     Medline TA:  Indian J Exp Biol     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  833-4     Citation Subset:  IM    
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MeSH Terms
Drug Interactions
Edetic Acid / toxicity*
Escherichia coli / drug effects*,  growth & development
Trialkyltin Compounds / toxicity*
Reg. No./Substance:
0/Trialkyltin Compounds; 60-00-4/Edetic Acid; 688-73-3/tributyltin

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