Document Detail


Interaction of COP1 and UVR8 regulates UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis.
MedLine Citation:
PMID:  19165148     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The ultraviolet-B (UV-B) portion of the solar radiation functions as an environmental signal for which plants have evolved specific and sensitive UV-B perception systems. The UV-B-specific UV RESPONSE LOCUS 8 (UVR8) and the multifunctional E3 ubiquitin ligase CONSTITUTIVELY PHOTOMORPHOGENIC 1 (COP1) are key regulators of the UV-B response. We show here that uvr8-null mutants are deficient in UV-B-induced photomorphogenesis and hypersensitive to UV-B stress, whereas overexpression of UVR8 results in enhanced UV-B photomorphogenesis, acclimation and tolerance to UV-B stress. By using sun simulators, we provide evidence at the physiological level that UV-B acclimation mediated by the UV-B-specific photoregulatory pathway is indeed required for survival in sunlight. At the molecular level, we demonstrate that the wild type but not the mutant UVR8 and COP1 proteins directly interact in a UV-B-dependent, rapid manner in planta. These data collectively suggest that UV-B-specific interaction of COP1 and UVR8 in the nucleus is a very early step in signalling and responsible for the plant's coordinated response to UV-B ensuring UV-B acclimation and protection in the natural environment.
Authors:
Jean-Jacques Favory; Agnieszka Stec; Henriette Gruber; Luca Rizzini; Attila Oravecz; Markus Funk; Andreas Albert; Catherine Cloix; Gareth I Jenkins; Edward J Oakeley; Harald K Seidlitz; Ferenc Nagy; Roman Ulm
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-01-22
Journal Detail:
Title:  The EMBO journal     Volume:  28     ISSN:  1460-2075     ISO Abbreviation:  EMBO J.     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-03-05     Completed Date:  2009-03-27     Revised Date:  2013-06-02    
Medline Journal Info:
Nlm Unique ID:  8208664     Medline TA:  EMBO J     Country:  England    
Other Details:
Languages:  eng     Pagination:  591-601     Citation Subset:  IM    
Affiliation:
Faculty of Biology, Institute of Biology II, University of Freiburg, Freiburg, Germany.
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MeSH Terms
Descriptor/Qualifier:
Acclimatization
Arabidopsis / physiology*
Arabidopsis Proteins / genetics,  physiology*
Chromosomal Proteins, Non-Histone / genetics,  physiology*
Gene Expression Regulation, Plant
Hypocotyl / growth & development,  physiology
Mutation
Protein Binding
Signal Transduction / physiology
Stress, Physiological
Sunlight
Ultraviolet Rays*
Grant Support
ID/Acronym/Agency:
//Biotechnology and Biological Sciences Research Council; //Howard Hughes Medical Institute
Chemical
Reg. No./Substance:
0/Arabidopsis Proteins; 0/Chromosomal Proteins, Non-Histone; 0/Uvr8 protein, Arabidopsis; 0/constitutive photomorphogenic 1 protein, Arabidopsis
Comments/Corrections

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