Document Detail


Inter-species hemorheologic differences in arterial and venous blood.
MedLine Citation:
PMID:  20134090     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Hemorheologic factors such as red blood cell (RBC) aggregation and deformability differ according to species. In many comparative hemorheologic studies, only venous blood samples have been used for measurements. There is little published information comparing arterial and venous blood differences between species. We compared hemorheologic factors in arterial and venous blood in rats, dogs and humans. METHODS: Nineteen dogs and 12 rats were used. Human blood was obtained from 12 healthy volunteers. Blood gas analysis, hematocrit and elongation index which represents RBC deformability were measured in arterial and venous blood samples. The critical shear stress and aggregation index, both of which represent RBC aggregation, were also measured in arterial and venous blood. RESULTS: There were no arterial or venous differences in hematocrit, critical shear stress, or elongation index in dogs. In rats, RBC aggregation was not measurable. The hematocrit and elongation index of arterial blood were significantly lower than those of venous blood in rats. There were no arterial or venous differences in hematocrit, aggregation index, or elongation index in humans. CONCLUSION: Arterial and venous hemorheologic factors differed depending on the species. Further standardization is necessary for the measurement of hemorheologic variables.
Authors:
Kuk Hui Son; Choon Hak Lim; Eun Joo Song; Kyung Sun; Ho Sung Son; Sung Ho Lee
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical hemorheology and microcirculation     Volume:  44     ISSN:  1875-8622     ISO Abbreviation:  Clin. Hemorheol. Microcirc.     Publication Date:  2010  
Date Detail:
Created Date:  2010-02-05     Completed Date:  2010-04-29     Revised Date:  2010-06-24    
Medline Journal Info:
Nlm Unique ID:  9709206     Medline TA:  Clin Hemorheol Microcirc     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  27-33     Citation Subset:  IM    
Affiliation:
Department of Thoracic and Cardiovascular Surgery, Korea University Medical Center, Seoul, Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Arteries*
Dogs
Erythrocyte Aggregation*
Erythrocyte Deformability*
Hematocrit
Hemorheology*
Humans
Male
Rats
Reference Values
Species Specificity
Veins*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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