Document Detail

Inter- and intra-individual variation of carbon monoxide production in young healthy males.
MedLine Citation:
PMID:  663542     Owner:  NLM     Status:  MEDLINE    
Duplicate studies of endogenous CO production (Vco) were performed in three groups of young healthy males. In group A (eleven subjects) Vco studies were performed with an interval of approximately 1 week. In group B (ten subjects) duplicate studies were done on the same day and in group C (ten subjects) duplicate studies were also done on the same day but with the subjects strictly resting between determinations. The error of the single determination estimated from duplicate measurements (formula: see text) was +/-4.3 mumol/mmol (TBH = total body haem) in group A and +/-3.7 and +/-1.0 in group B and C, respectively. Thus the intra-individual variation in Vco was considerably diminished when the duplicate determinations were performed with the subjects strictly resting between determinations. A possible explanation for this might be less variation in blood flow or metabolic processes in tissues engaged in haem breakdown in the resting group compared with the other groups.
B Werner
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of clinical and laboratory investigation     Volume:  38     ISSN:  0036-5513     ISO Abbreviation:  Scand. J. Clin. Lab. Invest.     Publication Date:  1978 May 
Date Detail:
Created Date:  1978-08-14     Completed Date:  1978-08-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404375     Medline TA:  Scand J Clin Lab Invest     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  199-202     Citation Subset:  IM    
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MeSH Terms
Carbon Monoxide / biosynthesis*,  blood
Carboxyhemoglobin / analysis
Oxygen Consumption
Tidal Volume
Reg. No./Substance:
630-08-0/Carbon Monoxide; 9061-29-4/Carboxyhemoglobin

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