Document Detail


Inter-alpha-trypsin inhibitor polymorphism. An improved phenotyping procedure and two new alleles.
MedLine Citation:
PMID:  7528045     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Serum samples treated with chondroitinase ABC and sialidase were investigated for the detection of inter-alpha-trypsin inhibitor (ITI) polymorphism. The improved phenotyping procedure has proved to be the most practical method for ITI phenotyping. The ITI allele frequencies were examined in 2 population samples from Japanese (n = 365) and Thais (n = 150). Three common alleles, ITI*1, ITI*2, and ITI*3 were identified in both populations, but the Thai population showed a higher frequency of ITI*1 and a lower frequency of ITI*3. Two new alleles were found, which were tentatively denoted ITI*Y and ITI*T. The ITI*T allele frequency in Thais was 0.047.
Authors:
A Harada; K Umetsu; T Suzuki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of legal medicine     Volume:  107     ISSN:  0937-9827     ISO Abbreviation:  Int. J. Legal Med.     Publication Date:  1994  
Date Detail:
Created Date:  1995-01-25     Completed Date:  1995-01-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9101456     Medline TA:  Int J Legal Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  25-8     Citation Subset:  IM    
Affiliation:
Department of Forensic Medicine, Yamagata University School of Medicine, Japan.
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MeSH Terms
Descriptor/Qualifier:
Alleles*
Alpha-Globulins / genetics*
Gene Frequency / genetics
Genetics, Population
Humans
Japan
Phenotype*
Polymorphism, Genetic / genetics*
Thailand
Trypsin Inhibitors / genetics*
Chemical
Reg. No./Substance:
0/Alpha-Globulins; 0/Trypsin Inhibitors; 39346-44-6/inter-alpha-inhibitor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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