Document Detail


Intensive intravenous treatment of ulcerative colitis.
MedLine Citation:
PMID:  3930339     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two hundred four courses of intensive intravenous treatment were given to 158 patients with ulcerative colitis. The remission rates in the severe, moderate, or mild attacks were 55.7%, 86.9%, and 91.8%. Total colitis had a great impact on the results, especially in severe attacks. Of these patients, 52.8% were operated on within 3 wk. The relapse rate was exponential, and during the first year 48.1% of the patients in remission relapsed. The extent of the colitis, severity of the attack, or duration of intensive intravenous treatment had no influence on the time of relapse. Twelve patients with chronic continuous disease were given intensive intravenous treatment. No long-term benefit was seen in patients with total ulcerative colitis, but half of those with less extensive colitis showed a good to excellent response to treatment.
Authors:
G Järnerot; P Rolny; H Sandberg-Gertzén
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gastroenterology     Volume:  89     ISSN:  0016-5085     ISO Abbreviation:  Gastroenterology     Publication Date:  1985 Nov 
Date Detail:
Created Date:  1985-11-15     Completed Date:  1985-11-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0374630     Medline TA:  Gastroenterology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1005-13     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Anti-Bacterial Agents / therapeutic use
Betamethasone / therapeutic use
Chronic Disease
Colectomy
Colitis, Ulcerative / pathology,  surgery,  therapy*
Female
Follow-Up Studies
Humans
Male
Middle Aged
Parenteral Nutrition, Total*
Prednisolone / therapeutic use
Recurrence
Sigmoidoscopy
Time Factors
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 378-44-9/Betamethasone; 50-24-8/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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