Document Detail

Intensive exercise training during bed rest attenuates deconditioning.
MedLine Citation:
PMID:  9044224     Owner:  NLM     Status:  MEDLINE    
A 30-d 6 degrees head-down bed rest project was conducted to evaluate variable high-intensity, short-duration, isotonic cycle ergometer exercise (ITE) training and high-intensity intermittent resistive isokinetic exercise (IKE) training regimens designed to maintain peak VO2 and muscle mass, strength, and endurance at ambulatory control levels throughout prolonged bed rest. Other elements of the deconditioning (adaptive) syndrome, such as proprioception, psychological performance, hypovolemia, water balance, body composition, and orthostatic tolerance, were also measured. Major findings are summarized in this paper. Compared with response during bed rest of the no exercise (NOE) control group: the ITE training regimen (a) maintained work capacity (peak VO2), (b) maintained plasma and red cell volumes (c) induced positive body water balance, (d) decreased quality of sleep and mental concentration, and (e) had no effect on the decrease in orthostatic tolerance; the IKE training regimen (f) attenuated the decrease in peak VO2 by 50%, (g) attenuated loss of red cell volume by 40% but had no effect on loss of plasma volume, (h) induced positive body water balance, (i) had no adverse effect on quality of sleep or concentration, and (j) had no effect on the decrease in orthostatic tolerance. These findings suggest that various elements of the deconditioning syndrome can be manipulated by duration and intensity of ITE or IKE training regimens and that several different training protocols will be required to maintain or restore physiological and psychological performance of individuals confined to prolonged bed rest.
J E Greenleaf
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Medicine and science in sports and exercise     Volume:  29     ISSN:  0195-9131     ISO Abbreviation:  Med Sci Sports Exerc     Publication Date:  1997 Feb 
Date Detail:
Created Date:  1997-04-30     Completed Date:  1997-04-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8005433     Medline TA:  Med Sci Sports Exerc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  207-15     Citation Subset:  IM; S    
Laboratory for Human Environmental Physiology, NASA, Ames Research Center, Moffett Field, CA 94035-1000, USA.
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MeSH Terms
Adaptation, Physiological / physiology*
Bed Rest / adverse effects*,  psychology
Cardiac Output / physiology
Cardiac Volume / physiology
Cardiovascular Deconditioning / physiology*
Exercise Therapy*
Tilt-Table Test
Water-Electrolyte Balance / physiology
J E Greenleaf / ARC

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