| Intensive chemotherapy for non-localised Burkitt's lymphoma. | |
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MedLine Citation:
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PMID: 3777984 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Between 1982 and 1984, 24 consecutively diagnosed children from Iraq with non-localised Burkitt lymphoma (Murphy stages II, III, and IV) were eligible for treatment with a multi-drug rotating chemotherapy schedule. This schedule was intensive and included early treatment directed at the central nervous system but was of only six months' duration and fairly inexpensive compared with schedules recently advocated for use in the developed world. Some patients had 'debulking' abdominal surgery, but no radiation treatment was used. There were a number of complications related to early treatment, some of them fatal, but of 13 patients entering complete remission 12 are long term survivors who are free of disease and, hopefully, cured. These results represent a substantial improvement over our experience before 1982 (6.9% survival). A similar treatment approach might be adopted by other centres, especially those in developing countries where cancer accounts for a rising proportion of childhood death but whose resources are limited. |
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Authors:
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A Al-Attar; J Pritchard; T Al-Saleem; M Al-Naimi; N Alash; A Attra |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Archives of disease in childhood Volume: 61 ISSN: 1468-2044 ISO Abbreviation: Arch. Dis. Child. Publication Date: 1986 Oct |
Date Detail:
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Created Date: 1986-12-18 Completed Date: 1986-12-18 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0372434 Medline TA: Arch Dis Child Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1013-9 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antineoplastic Combined Chemotherapy Protocols
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adverse effects,
therapeutic use* Burkitt Lymphoma / drug therapy*, mortality, pathology Child Child, Preschool Female Humans Male Neoplasm Staging |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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