Document Detail


[Intensive care treatment for neuroleptic malignant syndrome].
MedLine Citation:
PMID:  20665353     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a case of severe neuroleptic malignant syndrome developing in a 28-year-old female patient following deliberate self-poisoning with atypical antipsychotic drugs and serotonin reuptake inhibitors. Because of an increasing loss of consciousness she was rapidly transferred to an Intensive Care Unit. Following this, she became progressively febrile associated with rhabdomyolysis and life-threatening organ dysfunctions. Due to fast diagnosis and immediate therapy the patient was treated successfully. This article describes etiology, pathophysiology and symptoms of neuroleptic malignant syndrome. In addition therapeutic options are discussed.
Authors:
Mario Hensel; Klaus Böhler; Rudolf Marnitz; Christian Binder; Michael von Brevern
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Publication Detail:
Type:  Case Reports; English Abstract; Journal Article     Date:  2010-07-21
Journal Detail:
Title:  Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS     Volume:  45     ISSN:  1439-1074     ISO Abbreviation:  Anasthesiol Intensivmed Notfallmed Schmerzther     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-28     Completed Date:  2010-11-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9109478     Medline TA:  Anasthesiol Intensivmed Notfallmed Schmerzther     Country:  Germany    
Other Details:
Languages:  ger     Pagination:  448-55     Citation Subset:  IM    
Copyright Information:
(c) Georg Thieme Verlag Stuttgart-New York.
Affiliation:
Abteilung für Anästhesiologieund Intensivmedizin, Park-Klinik Weissensee, Berlin. hensel@park-klinik.com
Vernacular Title:
Intensivmedizinisches Management des malignen neuroleptischen Syndroms. Literaturübersicht mit Fallbeispiel.
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MeSH Terms
Descriptor/Qualifier:
Adult
Antidepressive Agents / adverse effects,  therapeutic use
Antipsychotic Agents / adverse effects,  therapeutic use
Benzodiazepines / adverse effects,  therapeutic use
Bipolar Disorder / complications,  drug therapy
Coma / chemically induced
Creatine Kinase / blood
Dantrolene / therapeutic use
Female
Humans
Intensive Care*
Muscle Relaxants, Central / therapeutic use
Myoglobin / blood
Neuroleptic Malignant Syndrome / diagnosis,  drug therapy,  therapy*
Sertraline / adverse effects,  therapeutic use
Treatment Outcome
Chemical
Reg. No./Substance:
0/Antidepressive Agents; 0/Antipsychotic Agents; 0/Muscle Relaxants, Central; 0/Myoglobin; 12794-10-4/Benzodiazepines; 132539-06-1/olanzapine; 7261-97-4/Dantrolene; 79617-96-2/Sertraline; EC 2.7.3.2/Creatine Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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