Document Detail

Intensity of antiplatelet therapy and percutaneous coronary intervention.
MedLine Citation:
PMID:  20948699     Owner:  NLM     Status:  In-Data-Review    
Thienopyridine derivatives such as clopidogrel have been shown to reduce the incidence of death in patients undergoing percutaneous coronary intervention when used in conjunction with aspirin. Recently, a new thienopyridine, prasugrel, significantly reduced the primary endpoint of cardiovascular death, non-fatal myocardial infarction or non-fatal stroke to 9.9% compared to 12.1% for clopidogrel. Prasugrel has been shown to be more efficacious than clopidigrel in reducing ischemic events and stent thrombosis, but does cause more life-threatening bleeding in patients undergoing percutaneous coronary intervention.
Wilbert S Aronow
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Publication Detail:
Type:  Journal Article     Date:  2009-01-21
Journal Detail:
Title:  F1000 medicine reports     Volume:  1     ISSN:  1757-5931     ISO Abbreviation:  F1000 Med Rep     Publication Date:  2009  
Date Detail:
Created Date:  2010-10-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101506841     Medline TA:  F1000 Med Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  -    
Department of Medicine, Divisions of Cardiology, Geriatrics, and Pulmonary/Critical Care, New York Medical College Valhalla, New York 10595 USA.
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