Document Detail

Intensification of fetal and maternal surveillance in pregnant women with hypertensive disorders.
MedLine Citation:
PMID:  9639216     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To examine the need to intensify fetal and maternal surveillance in pregnant women with mild pregnancy hypertension. METHODS: The multi-center cohort study in 2413 healthy nulliparae analyzed differences in hypertension-related adverse events (small-for-gestational age, perinatal mortality, eclampsia, abruptio placentae and HELLP syndrome) according to maximum diastolic blood pressure and proteinuria. RESULTS: Compared to the reference group (diastolic blood pressure 70-85 mmHg) (n = 1882) the relative risks of adverse fetal and maternal outcome in 34 proteinuric hypertensive women were 8.9 (95% CI 3.3-24.1) and 41.5 (95% CI 9.7-178.4), respectively. In 203 non-proteinuric women with a maximum diastolic blood pressure of > or = 95 mmHg only the relative risk of adverse maternal outcome was increased (11.6, 95% CI 3.1-42.8), but it was not increased in 230 non-proteinuric women with a maximum diastolic of 90 mmHg. CONCLUSIONS: Intensified surveillance in women with mild pregnancy hypertension is not indicated and should be reserved for groups with increased fetal and maternal risk.
M Knuist; G J Bonsel; H A Zondervan; P E Treffers
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  61     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  1998 May 
Date Detail:
Created Date:  1998-08-27     Completed Date:  1998-08-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  127-33     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Academic Medical Center, University of Amsterdam, The Netherlands.
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MeSH Terms
Pregnancy Complications, Cardiovascular*
Pregnancy Outcome*
Prospective Studies
Proteinuria / complications,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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