| Integrin and matrix metalloprotease dual-targeting with an MMP substrate-RGD conjugate. | |
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MedLine Citation:
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PMID: 23196995 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A fluorescent clustered RGD-containing ligand encompassing an MMP substrate was designed and successfully used in vivo for the dual-targeting of α(V)β(3) integrin receptors and MMP-9 extracellular proteases in the tumor region. |
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Authors:
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Christiane H F Wenk; Véronique Josserand; Pascal Dumy; Jean-Luc Coll; Didier Boturyn |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-11-29 |
Journal Detail:
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Title: Organic & biomolecular chemistry Volume: - ISSN: 1477-0539 ISO Abbreviation: Org. Biomol. Chem. Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-11-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101154995 Medline TA: Org Biomol Chem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Département de Chimie Moléculaire, CNRS: UMR 5250, ICMG FR 2607, Grenoble cedex 9, France. didier.boturyn@ujf-grenoble.fr. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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