Document Detail


Integrin and matrix metalloprotease dual-targeting with an MMP substrate-RGD conjugate.
MedLine Citation:
PMID:  23196995     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A fluorescent clustered RGD-containing ligand encompassing an MMP substrate was designed and successfully used in vivo for the dual-targeting of α(V)β(3) integrin receptors and MMP-9 extracellular proteases in the tumor region.
Authors:
Christiane H F Wenk; Véronique Josserand; Pascal Dumy; Jean-Luc Coll; Didier Boturyn
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-29
Journal Detail:
Title:  Organic & biomolecular chemistry     Volume:  -     ISSN:  1477-0539     ISO Abbreviation:  Org. Biomol. Chem.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101154995     Medline TA:  Org Biomol Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Département de Chimie Moléculaire, CNRS: UMR 5250, ICMG FR 2607, Grenoble cedex 9, France. didier.boturyn@ujf-grenoble.fr.
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