Document Detail


Integration of the thiol redox status with cytokine response to physical training in professional basketball players.
MedLine Citation:
PMID:  19537921     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present study was designed to evaluate the plasma markers of reactive oxygen species (ROS) activity and cytokines, and their relationship with thiol redox status of basketball players during training. Sixteen professional players of the Polish Basketball Extraleague participated in the study. The study was performed during the preparatory period and the play-off round. Markers of ROS activity (lipid peroxidation TBARS, protein carbonylation PC) and reduced glutathione (GSH) demonstrated regularity over time, i.e. TBARS, PC and GSH were elevated at the beginning and decreased at the end of training periods. Oxidized glutathione (GSSG) was not affected by exercise training. Thiol redox status (GSH(total)-2GSSG/GSSG) correlated with TBARS and PC in both training periods. The level of interleukin-6 (IL-6) was increased and positively correlated with thiol redox (r=0.423) in the preparatory period, whereas tumor necrosis factor alpha (TNFalpha) was increased and inversely correlated with thiol redox (r= 0.509) in the play-off round. The present study showed significant shifts in markers of ROS activity, thiol redox status and inflammatory mediators (IL-6, TNFalpha) following professional sport training as well as correlation between changes in thiol redox and cytokine response.
Authors:
A Zembron-Lacny; M Slowinska-Lisowska; A Ziemba
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-06-19
Journal Detail:
Title:  Physiological research / Academia Scientiarum Bohemoslovaca     Volume:  59     ISSN:  0862-8408     ISO Abbreviation:  Physiol Res     Publication Date:  2010  
Date Detail:
Created Date:  2010-05-20     Completed Date:  2010-08-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9112413     Medline TA:  Physiol Res     Country:  Czech Republic    
Other Details:
Languages:  eng     Pagination:  239-45     Citation Subset:  IM    
Affiliation:
University of Physical Education Poznan, Faculty of Physical Culture Gorzow Wlkp., Department of Biochemistry, Gorzow Wlkp., Poland. agzem@gorzow.home.pl
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MeSH Terms
Descriptor/Qualifier:
Adult
Basketball / physiology*
Biological Markers / blood
Creatine Kinase / blood
Glutathione Disulfide / metabolism
Humans
Interleukin-6 / blood*
Lipid Peroxidation / physiology
Male
Oxidation-Reduction
Oxidative Stress / physiology
Physical Fitness / physiology*
Sulfhydryl Compounds / metabolism*
Thiobarbituric Acid Reactive Substances / metabolism
Tumor Necrosis Factor-alpha / blood*
Chemical
Reg. No./Substance:
0/Biological Markers; 0/IL6 protein, human; 0/Interleukin-6; 0/Sulfhydryl Compounds; 0/Thiobarbituric Acid Reactive Substances; 0/Tumor Necrosis Factor-alpha; 27025-41-8/Glutathione Disulfide; EC 2.7.3.2/Creatine Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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