Document Detail


Integration of exercise response and allometric scaling in endotherms.
MedLine Citation:
PMID:  23328533     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The relationship between heart beat frequency and the rate of oxygen consumption for different species of birds and mammals is influenced by body size, the type of exercise being undertaken and its intensity. Here a model is presented combining allometric scaling and exercise-induced variations in oxygen consumption and blood flow, when birds and mammals undergo their primary mode of locomotion. Novel relationships, common to the regulatory systems of all endotherms, are found to relate the rate of oxygen consumption, heart-rate, body and heart mass in 24 species of endotherms spanning 5 orders of body mass. We show that these relationships can be derived from linearity between heart-rate and the arteriovenous oxygen difference, present in data from exercise-attuned humans. We find that the metabolic rate of endotherms undergoing their primary mode of locomotion across a range of exercise intensities is quadratically related to heart-rate and that body mass is inferior to heart mass as a predictive scaling variable. The model facilitates graphical comparisons between species, and enables metabolic costs to be extrapolated from heart-rate data whenever direct measurements of oxygen consumption prove prohibitively challenging.
Authors:
Charles M Bishop; Robin J Spivey
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Publication Detail:
Type:  Journal Article     Date:  2013-01-15
Journal Detail:
Title:  Journal of theoretical biology     Volume:  323     ISSN:  1095-8541     ISO Abbreviation:  J. Theor. Biol.     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-18     Completed Date:  2013-09-30     Revised Date:  2014-10-14    
Medline Journal Info:
Nlm Unique ID:  0376342     Medline TA:  J Theor Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  11-9     Citation Subset:  IM    
Copyright Information:
Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Circulation / physiology
Body Size / physiology*
Body Weight / physiology
Exercise / physiology*
Humans
Models, Biological
Oxygen / blood
Oxygen Consumption / physiology
Grant Support
ID/Acronym/Agency:
BB/F015615/1//Biotechnology and Biological Sciences Research Council
Chemical
Reg. No./Substance:
S88TT14065/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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