Document Detail

Integration of cardiorespiratory responses in the ventrolateral medulla.
MedLine Citation:
PMID:  2616783     Owner:  NLM     Status:  MEDLINE    
Interventions confined to the region adjacent to the VMS can produce both respiratory and circulatory effects. Although it has been suggested that both breathing and vasomotor changes arise from the same neural elements near the VMS, our own investigations indicate that the neurons involved are closely linked but not identical. This belief is supported by recent studies which show that AII and angiotensin antagonists microinjected into the rostral portion of the VMS can significantly modify blood pressure and respiration but can produce effects of different sign. These observations, coupled with previous studies of the VMS, indicate the possibility that regions near the VMS may contribute to integration of circulatory and respiratory responses.
N S Cherniack; E M Adams; N R Prabhakar; M Haxhiu; J Mitra
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Progress in brain research     Volume:  81     ISSN:  0079-6123     ISO Abbreviation:  Prog. Brain Res.     Publication Date:  1989  
Date Detail:
Created Date:  1990-03-09     Completed Date:  1990-03-09     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0376441     Medline TA:  Prog Brain Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  215-20     Citation Subset:  IM    
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MeSH Terms
Blood Pressure / physiology*
Medulla Oblongata / physiology*
Respiration / physiology*

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