Document Detail

Integrating prevention of mother-to-child HIV transmission into routine antenatal care: the key to program expansion in Cameroon.
MedLine Citation:
PMID:  16280706     Owner:  NLM     Status:  MEDLINE    
With funds from Elizabeth Glaser Pediatric AIDS Foundation, the Cameroon Baptist Convention Health Board implemented a program to prevent mother-to-child transmission of HIV-1 (PMTCT) as part of its routine antenatal care, with single-dose maternal and infant peripartum nevirapine (NVP) prophylaxis of HIV-positive mothers and their babies. Nurses, midwives, nurse aides, and trained birth attendants counseled pregnant women, obtained risk factor data, and offered free HIV testing with same-day results. From February 2000 through December 2004, this program rapidly expanded to 115 facilities in 6 of Cameroon's 10 provinces, not only to large hospitals but to remote health centers staffed by trained birth attendants. We trained 690 health workers in PMTCT and counseled 68,635 women, 91.9% of whom accepted HIV testing. Of 63,094 women tested, 8.7% were HIV-1-positive. Independent risk factors for HIV-1 infection included young age at first sexual intercourse, multiple sex partners, and positive syphilis serology (P < 0.001 for each). We counseled 98.7% of positive and negative mothers on a posttest basis. Of 5550 HIV-positive mothers, we counseled 5433 (97.9%) on single-dose NVP prophylaxis. Consistent training and programmatic support contributed to rapid upscaling and high uptake and counseling rates.
Thomas K Welty; Marc Bulterys; Edith R Welty; Pius M Tih; George Ndikintum; Godlove Nkuoh; Joseph Nkfusai; Janet Kayita; John N Nkengasong; Catherine M Wilfert
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of acquired immune deficiency syndromes (1999)     Volume:  40     ISSN:  1525-4135     ISO Abbreviation:  J. Acquir. Immune Defic. Syndr.     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-11-10     Completed Date:  2006-01-10     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  100892005     Medline TA:  J Acquir Immune Defic Syndr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  486-93     Citation Subset:  IM; X    
Cameroon Baptist Convention Health Board, Nso, Northwest Province, Cameroon.
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MeSH Terms
Age Factors
Anti-HIV Agents / administration & dosage,  therapeutic use
HIV Infections / diagnosis,  prevention & control*,  transmission*
Infant, Newborn
Infectious Disease Transmission, Vertical / prevention & control*
Nevirapine / administration & dosage,  therapeutic use
Patient Education as Topic
Pregnancy Complications, Infectious*
Prenatal Care / methods*
Reverse Transcriptase Inhibitors / administration & dosage,  therapeutic use
Risk Factors
Sexual Behavior
Reg. No./Substance:
0/Anti-HIV Agents; 0/Reverse Transcriptase Inhibitors; 129618-40-2/Nevirapine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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