| Integrating existing natural language processing tools for medication extraction from discharge summaries. | |
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MedLine Citation:
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PMID: 20819857 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To develop an automated system to extract medications and related information from discharge summaries as part of the 2009 i2b2 natural language processing (NLP) challenge. This task required accurate recognition of medication name, dosage, mode, frequency, duration, and reason for drug administration. DESIGN: We developed an integrated system using several existing NLP components developed at Vanderbilt University Medical Center, which included MedEx (to extract medication information), SecTag (a section identification system for clinical notes), a sentence splitter, and a spell checker for drug names. Our goal was to achieve good performance with minimal to no specific training for this document corpus; thus, evaluating the portability of those NLP tools beyond their home institution. The integrated system was developed using 17 notes that were annotated by the organizers and evaluated using 251 notes that were annotated by participating teams. MEASUREMENTS: The i2b2 challenge used standard measures, including precision, recall, and F-measure, to evaluate the performance of participating systems. There were two ways to determine whether an extracted textual finding is correct or not: exact matching or inexact matching. The overall performance for all six types of medication-related findings across 251 annotated notes was considered as the primary metric in the challenge. RESULTS: Our system achieved an overall F-measure of 0.821 for exact matching (0.839 precision; 0.803 recall) and 0.822 for inexact matching (0.866 precision; 0.782 recall). The system ranked second out of 20 participating teams on overall performance at extracting medications and related information. CONCLUSIONS: The results show that the existing MedEx system, together with other NLP components, can extract medication information in clinical text from institutions other than the site of algorithm development with reasonable performance. |
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Authors:
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Son Doan; Lisa Bastarache; Sergio Klimkowski; Joshua C Denny; Hua Xu |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Journal of the American Medical Informatics Association : JAMIA Volume: 17 ISSN: 1527-974X ISO Abbreviation: J Am Med Inform Assoc Publication Date: 2010 Sep-Oct |
Date Detail:
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Created Date: 2010-09-07 Completed Date: 2010-11-15 Revised Date: 2011-09-13 |
Medline Journal Info:
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Nlm Unique ID: 9430800 Medline TA: J Am Med Inform Assoc Country: United States |
Other Details:
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Languages: eng Pagination: 528-31 Citation Subset: IM |
Affiliation:
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Department of Biomedical Informatics, Vanderbilt University, School of Medicine, Nashville, TN, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Electronic Health Records* Humans Information Storage and Retrieval / methods* Natural Language Processing* Patient Discharge* Pharmaceutical Preparations* Systems Integration |
| Grant Support | |
ID/Acronym/Agency:
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R01 CA141307-03/CA/NCI NIH HHS; R01-LM007995-05/LM/NLM NIH HHS; R01CA141307-01/CA/NCI NIH HHS; U01HG004603/HG/NHGRI NIH HHS; U54LM008748/LM/NLM NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Pharmaceutical Preparations |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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