Document Detail


Integrating epitope data into the emerging web of biomedical knowledge resources.
MedLine Citation:
PMID:  17479127     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The recognition of immune epitopes is an important molecular mechanism of the vertebrate immune system to discriminate between self and non-self. Increasing amounts of data on immune epitopes are becoming available due to technological advances in epitope-mapping techniques and the availability of genomic information for pathogens. Organizing this data poses a challenge that is similar to the successful effort that was required to organize genomic data, which needed the establishment of centralized databases that complement the primary literature to make the data readily accessible and searchable by researchers. As described in this Innovation article, the Immune Epitope Database and Analysis Resource aims to achieve the same for the more complex and context-dependent information on immune epitopes, and to integrate this data with existing and emerging knowledge resources.
Authors:
Bjoern Peters; Alessandro Sette
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Nature reviews. Immunology     Volume:  7     ISSN:  1474-1733     ISO Abbreviation:  Nat. Rev. Immunol.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-05-25     Completed Date:  2007-07-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101124169     Medline TA:  Nat Rev Immunol     Country:  England    
Other Details:
Languages:  eng     Pagination:  485-90     Citation Subset:  IM    
Affiliation:
La Jolla Institute for Allergy and Immunology, Division of Vaccine Discovery, 9420 Athena Circle, La Jolla, California 92037, USA.
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MeSH Terms
Descriptor/Qualifier:
Amino Acid Sequence
Animals
Database Management Systems
Databases, Genetic*
Epitopes / chemistry,  genetics*
Humans
Information Storage and Retrieval*
Internet
Molecular Sequence Data
Protein Structure, Tertiary
Chemical
Reg. No./Substance:
0/Epitopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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