| Integrated strategies for allogeneic blood saving in major elective surgery. | |
| | |
MedLine Citation:
|
PMID: 22019727 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND: Large use of allogeneic red blood cell concentrates (RBCc), albeit necessary in major surgery, may influence patients' outcome. DESIGN AND METHODS: We introduced an integrated strategy including patients' evaluation and supplementation associated with autologous blood collection and saving to support major elective surgery at our hospital since 2008. After 2years of stabilization of this approach, we analyzed the results obtained in 2010 in terms of allogeneic blood usage and reduction of transfusion of stored RBCc. RESULTS: Analyzing 2010 results we found that usage of total autologous RBCc units was increased by 2.2 folds, of "not stored" autologous RBCc units by 2.4 folds and of allogeneic RBCc unit transfusion reduced by 65%. The significant reduction in the number of transfused allogeneic RBCc units associated with the use of "fresher" blood could prevent patients' complications due to immunomodulation and biologic/metabolic disregulation. |
| | |
Authors:
|
Maria Beatrice Rondinelli; Francesco Pallotta; Sandro Rossetti; Francesco Musumeci; Antonio Menichetti; Franco Bianco; Marco Gaffi; Luca Pierelli |
Related Documents
:
|
10691317 - The blood spot thyrotropin method is not adequate to screen for hypothyroidism in the e... 2240857 - The inactivation of antithrombin iii by serum elastase in patients with surgical infect... 3386507 - Hemolysis during triathlon races: its relation to race distance. 22263107 - Intracranial blood flow velocity in patients with β-thalassemia intermedia using trans... 12518877 - Evaluation of transcutaneous doppler ultrasonography for the measurement of blood flow ... 8570857 - Neuropeptide immunoreactivity and co-existence in cardiovascular nerves and autonomic g... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-10-21 |
Journal Detail:
|
Title: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis Volume: - ISSN: 1473-0502 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
|
Created Date: 2011-10-24 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101095653 Medline TA: Transfus Apher Sci Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
|
Department of Transfusion Medicine, San Camillo Forlanini Hospital, Rome, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Allogeneic Hematopoietic Stem Cell Transplantation for Philadelphia Positive Acute Lymphoblastic Leu...
Next Document: Acute normovolemic hemodilution.